AGAP2 (Arf GAP with GTP-binding protein-like domain, Ankyrin repeat and PH domain 2) isoform 2 is a protein that belongs to the Arf GAP (GTPase activating protein) protein family. These proteins act as GTPase switches for Arfs, which are Ras superfamily members, being therefore involved in signaling regulation. Arf GAP proteins have been shown to participate in several cellular functions

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In Deutschland ist agap2 mit hochqualifizierten Ingenieuren, Naturwissenschaftlern und (approbierten) Pharmazeuten auf die Life Sciences spezialisiert. Unsere Kollegen unterstützen vielfältige Projekte operativ direkt beim Kunden vor Ort. 2017-02-16 · AGAP2-AS1 functions as an oncogenic lncRNA by interacting with LSD1 and EZH2 and suppressing CDKN1A (P21) and E-cadherin transcription. CONCLUSIONS: Taken together, these findings imply that AGAP2-AS1 upregulated by SP1 plays an important role in GC development and progression by suppressing P21 and E-cadherin, which suggests that AGAP2-AS1 is a potential diagnostic marker and therapeutic 216439 Ensembl ENSG00000135439 ENSMUSG00000025422 UniProt Q99490 Q3UHD9 RefSeq (mRNA) NM_001122772 NM_014770 NM_001033263 NM_001301014 RefSeq (protein) NP_001116244 NP_055585 NP_001028435 NP_001287943 Location (UCSC) Chr 12: 57.72 – 57.74 Mb Chr 10: 127.08 – 127.09 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 agap2 est un groupe européen d’ingénierie et de conseil opérationnel spécialisé dans l’industrie. About Press Copyright Contact us Creators Advertise Developers Terms Privacy Policy & Safety How YouTube works Test new features Press Copyright Contact us Creators agap2 Netherlands | 1.804 volgers op LinkedIn. Global presence, local action.

agap2 – a HIQ Consulting Brand « agap2 » – HIQ Consulting - a European operational consultancy and engineering group specialised in industry and IT. The Group assists its clients in speeding up their growth by helping them complete their projects.

Over the past years, we   Agap2 operates as an operational consultancy and engineering group specialised in industry and IT. Jan 23, 2019 AGAP2 (Arf GAP with GTP-binding protein-like domain, Ankyrin repeat and PH domain 2) isoform 2 is considered a proto-oncogene, but not  AGAP2 (also known as Arf-GAP with GTPase, ANK repeat and PH domain- containing protein 2) is a GTPase activating protein that inactivates Arf. The expression  Description. agap2 is a European operational consultancy and engineering group specialised in industry. We are always looking for talents! Read More.

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Mar 27, 2020 Long non-coding RNA (lncRNA) AGAP2‑AS1 has been reported to be a potential biomarker for a variety of cancer types, while its function in 

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Empenhada na inovação, a agap2IT está orientada para a criação de um verdadeiro valor para os seus Clientes e Consultores. A capacidade de intervir globalmente aliada à elevada experiência e know-how técnico, funcional e de negócio da equipa, garantem a excelência da resposta aos mais exigentes e complexos desafios. agap2 Sweden. The agap2 group is a European consulting company founded in 2005 and has since developed rapidly. Today, agap2 has 40+ offices in 11 European countries and 5,500+ employees. agap2 opened the office in Stockholm in 2017 and we currently work in Stockholm, Uppsala, Södertälje and Strängnäs.
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About Press Copyright Contact us Creators Advertise Developers Terms Privacy Policy & Safety How YouTube works Test new features Press Copyright Contact us Creators agap2 Netherlands | 1.804 volgers op LinkedIn. Global presence, local action. | agap2 is founded in September 2005. In ten years, agap2 has grown to a qualified European Consultancy in the areas of Information Systems and a reference in the world of Banking, Insurance, Telecommunications, Industry, Pharmaceuticals and Energy.

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MyD88 was identified as a downstream target of AGAP2-AS1 and mediated the AGAP2-AS1-induced oncogenic effects. Mechanistically, the RIP assay revealed that AGAP2-AS1 could bind to CBP, a Groupe européen d’ingénierie et de conseil opérationnel spécialisé dans l’industrie et l'IT Une aventure humaine Dix ans après la création d’agap2 nous somme Learn about Agap2's Basel office. Search jobs.


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These proteins act as GTPase switches for Arfs, which are Ras superfamily members, being therefore involved in signaling regulation. Arf GAP proteins have been shown to participate in several cellular functions agap2 | 29.763 seguidores no LinkedIn.

De novo missense variants in the AGAP2 gene have previously been identified in ASD cases (De Rubeis et al., 2014; Iossifov et al., 2014). An additional de novo missense variant in this gene was identified by whole genome sequencing in an ASD proband from a multiplex family as part of the MSSNG initiative in Yuen et al., 2017.

Kunder som agap2 Sweden samarbetar med idag är bland annat Galderma, GE Healthcare, Octapharma och Recipharm.

Duration: Perennial. Growth Habit: Forb/herb. Native Status: L48 N. Data Source and Documentation  AGAP2 (ArfGAP with GTPase domain, ankyrin repeat and PH domain 2) is a GTPase/GTP-activating protein involved in the actin remodelling system and receptor  AGAP2 (Centaurin , gamma1), Authors: Chan Chi Bun, Ye Keqiang. Published in: Atlas Genet Cytogenet Oncol Haematol. Mar 5, 2021 AGAP2 (ArfGAP With GTPase Domain, Ankyrin Repeat And PH Domain 2) is a Protein Coding gene. Diseases associated with AGAP2 include  AGAP2 (Arf GAP with GTP-binding protein-like domain, Ankyrin repeat and PH domain 2) isoform 2 is a protein that belongs to the Arf GAP (GTPase activating  Overexpression of AGAP2 augments the activity of FAK, and concordantly, the knockdown of AGAP2 expression with RNA interference attenuates the FAK activity  Please enter in the blue-yellow side.